Product name:  Rivotril 2mg

Manufacturer: Roche Pharmaceuticals

Active substance: Clonazepam

Brand names: clonazepam

Dosage Strength(s): 0.5 MG, 2 MG

Quantity: 100 – 750 Tablets






Rivotril contains a medicine called Clonazepam. This belongs to a group of medicines called ‘benzodiazepines’.

Rivotril  is used to treat epilepsy in infants, children and adults.

– It lowers the number of fits (seizures) that you have.

– Any fits that you do have will be less serious.

Before you take Rivotril

Do not take Rivotril if:

you have had an allergic reaction to Rivotril, any other benzodiazepine medicine or any ingredients listed at the end of this leaflet

Some symptoms of an allergic reaction may include:

  • shortness of breath
  • wheezing or difficulty in breathing
  • swelling of the face, lips, tongue or other parts of the body
  • rash, itching or hives on the skin
  • you have severe and chronic lung disease
  • you have severe liver disease
  • you have an addiction to drugs or alcohol
  • the package is torn or shows signs of tampering
  • the expiry date (EXP) printed on the pack has passed.

If you take this medicine after the expiry date has passed it may not work as well.

Rivotril injection contains benzyl alcohol and must not be given to newborn babies, especially premature babies.

If you are not sure if you should be taking Rivotril, talk to your doctor.

Before you start to take it:

  • Your doctor must know about all the following before you start to take Rivotril.
  • if you are pregnant or plan to become pregnant
  • It is not known whether Rivotril is harmful to an unborn baby when taken by a pregnant woman. If there is a need to take Rivotril when you are pregnant your doctor will discuss the risks and benefits to you and the unborn baby.
  • if you are breastfeeding or plan to breastfeed

Rivotril may pass into the breast milk and cause drowsiness and/or feeding difficulties in the baby. Rivotril is not recommended for use while breastfeeding.

if you have any other health problems including:

  • liver, kidney or lung disease
  • high or low blood pressure
  • myasthenia gravis (severe muscle weakness)
  • sleep apnoea (a condition where you have temporary stops in breathing during sleep)
  • glaucoma (a condition where you have high pressure in the eye) depression, psychosis or schizophrenia and /or you have had depression or suicidal thoughts in the past.
  • porphyria (a rare blood pigment disorder)
  • a history of alcohol or drug abuse
  • if you drink alcohol

You should not drink alcohol while taking Rivotril. Alcohol may increase the effects of Rivotril and lead to serious side effects.

  • if you are lactose intolerant
  • if you are allergic to any other medicines, foods, dyes or preservatives.

Taking other medicines

Tell your doctor if you are taking any other medicines including any that you have bought without a prescription from a pharmacy, supermarket or health-food shop.

Some medicines may interfere with Rivotril. These medicines include:

  • sleeping tablets, sedatives or tranquillisers
  • some medicines for depression
  • other medicines to control epilepsy
  • medicines for allergies or colds such as antihistamines
  • pain relievers
  • muscle relaxants
  • anaesthetics
  • cimetidine – a medicine used to treat ulcers
  • disulfiram – a medicine used in alcohol abuse

These medicines may be affected by Rivotril or may affect how well Rivotril works. Your doctor or pharmacist can tell you what to do if you are taking any of these medicines. They also have a more complete list of medicines to be careful with or avoid while taking Rivotril.

If you have not told your doctor about any of the above, tell them before you start taking Rivotril.



Always take Rivotril exactly as your doctor has told you. You should check with your doctor if you are not sure.

– Your doctor will start you on a low dose of Rivotril and gradually increase it over 2 to 4 weeks until the right dose has been found for you.

– Your doctor will usually tell you to split your daily dose into three equal amounts which you will take at evenly spaced times throughout the day.

– If the daily dose cannot be split equally, take the largest dose at bedtime.

– Once your doctor has found the right dose for you, they may tell you to take Rivotril as a single dose in the evening.

Adults and children over 12 years

– The usual starting dose is 1 mg a day, or less.

– This will be increased gradually (usually to between 4 mg and 8 mg a

day). The maximum dose is 20 mg a day.

The elderly

– The usual starting dose is 0.5 mg a day, or less.

– This will be increased gradually (usually to between 4 mg and 8 mg a day). The maximum dose is 20 mg a day.

Infants (aged 0 to 1 year)

– The usual starting dose is 0.25 mg a day, or less.

– This will be increased gradually (usually to between 0.5 mg and 1 mg a day).

Small children (aged 1 to 5 years)

– The usual starting dose is 0.25 mg a day, or less.

– This will be increased gradually (usually to between 1 mg and 3 mg a day).

Older children (aged 5 to 12 years)

– The usual starting dose is 0.5 mg a day, or less.

– This will be increased gradually (usually to between 3 mg and 6 mg a day).

If you take more Rivotril than you should

– If you take more Rivotril than you should, talk to a doctor or go to a hospital straight away.

Take the medicine pack with you.

– If you take too many tablets, you may feel drowsy, sleepy, light-headed, have a lack of co-ordination or be less responsive than normal.

If you forget to take Rivotril

– If you forget to take a dose, skip the missed dose. Then take the next dose when it is due.

– Do not take a double dose (two doses at the same time) to make up for a forgotten dose.


Stopping Rivotril

If you receive long term treatment with Rivotril (are given the medicine for a long time) you may become dependent upon this medicine and get withdrawal symptoms .

– Do not stop taking your tablets without talking to your doctor. If you do, your fits may return and you may get withdrawal symptoms

– If the dose of Rivotril you take has to be reduced, or stopped, this must be done gradually. Your doctor will let you know how to do this.

If someone else takes your Rivotril tablets by mistake, they should talk to a doctor or go to a hospital straight away.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.



Like all medicines Rivotril can cause side effects, although not everybody will get them.

Important side effects to look out for:

  • Allergic reactions

If you get an allergic reaction, see a doctor straight away.

The signs may include:

– Sudden swelling of the throat, face, lips and mouth. This may make it difficult to breathe or swallow.

– Sudden swelling of the hands, feet and ankles.

– Skin rash or itching.

  • Effects on the heart

If you notice any of the following effects, see a doctor straight away.

The signs may include:

– Breathlessness, swelling of the ankles, cough, tiredness and a racing heart.

– Chest pain which may spread to your neck and shoulders and down your left arm.

  • Effects on behaviour

If you notice any of the following effects, talk to your doctor as they may want you to stop taking Rivotril. The signs may include:

– Being aggressive, excited, irritable, nervous, agitated, hostile or anxious.

– Problems sleeping, nightmares and vivid dreams.

– Mental problems such as seeing or hearing things that are not really there(hallucinations), delusions (believing in things that are not real) and problems with your speech.

– Types of fits (seizures) that you have not had before. Infants and children

– If an infant or small child is taking Rivotril, watch them carefully. This is because they could develop breathing problems, coughing or choking. This can be caused by too much saliva being made.

– Early puberty in children. This is reversible after stopping treatment with Rivotril.



Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.



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