Selected:

Nembutal Pentobarbital

$225.00$16,390.00

Sale!

Nembutal Pentobarbital

$225.00$16,390.00

Product name: Nembutal

Generic Name: Pentobarbital sodium

Brand Names: Nembutal Sodium

Dosage Strength(s): 50 MG, 100 MG

Quantity:

  • 1 – 24 Vials of 10ml, 20ml, 50ml Nembutal Pentobarbital Sodium
  • 50 – 450 Capsules of 50mg, 100mg Nembutal Pentobarbital Solution Capsules
Clear

Description

BUY  NEMBUTAL ONLINE

 

PRODUCT DESCRIPTION

Nembutal Sodium is a barbiturate (bar-BIT-chur-ate). This medicine slows the activity of your brain and nervous system.

Nembutal Sodium is used short-term as a sedative to treat insomnia, or to cause you to fall asleep for surgery. This medicine is also used as an emergency treatment for seizures.

Nembutal Sodium may also be used for purposes not listed in this medication guide.

The barbiturates are nonselective central nervous system depressants which are primarily used as sedative hypnotics and also anticonvulsants in subhypnotic doses. The barbiturates and their sodium salts are subject to control under the Federal Controlled Substances Act.

The sodium salts of amobarbital, pentobarbital, phenobarbital, and secobarbital are available as sterile parenteral solutions.

Barbiturates are substituted pyrimidine derivatives in which the basic structure common to these drugs is barbituric acid, a substance which has no central nervous system (CNS) activity. CNS activity is obtained by substituting alkyl, alkenyl, or aryl groups on the pyrimidine ring.

NEMBUTAL Sodium Solution (pentobarbital sodium injection) is a sterile solution for intravenous or intramuscular injection. Each mL contains pentobarbital sodium 50 mg, in a vehicle of propylene glycol, 40%, alcohol, 10% and water for injection, to volume. The pH is adjusted to approximately 9.5 with hydrochloric acid and/or sodium hydroxide.

 

DOSAGE METHOD

Usual Adult Dose for Insomnia

Oral capsules or elixir: 100 mg orally at bedtime.

Rectal suppository: 120 to 200 mg rectally.

Injection: 100 to 200 mg IM or IV.

Usual Adult Dose for Sedation

Oral capsules or elixir: 100 mg orally at bedtime.

Rectal suppository: 120 to 200 mg rectally.

Injection: 100 to 200 mg IM or IV.

Usual Pediatric Dose for Sedation

Procedural (moderate) sedation:

Oral:

Infants: 4 mg/kg orally followed by 2 to 4 mg/kg every 30 minutes if needed

Maximum dose: 8 mg/kg orally

Infants and Children:

IM: 2 to 6 mg/kg

IM Maximum dose: 100 mg

IV: Initial 1 to 2 mg/kg; additional doses of 1 to 2 mg/kg every 3 to 5 minutes to desired effect; usual effective total dose is 1 to 6 mg/kg

IV Maximum dose: 100 mg/dose Note: Patients receiving concurrent barbiturate therapy may require higher total mg/kg doses (up to 9 mg/kg).

Children:

Oral, Rectal:

Less than 4 years: 3 to 6 mg/kg

Maximum dose: 100 mg

Greater than or equal to 4 years: 1.5 to 3 mg/kg

Maximum dose: 100 mg

Adolescents: IV: 100 mg prior to procedure

Reduction of elevated ICP:

IV: Note: Intubation is required; dose should be adjusted based on hemodynamics, ICP, cerebral perfusion pressure, and EEG.

Low dose: Children and Adolescents: 5 mg/kg every 4 to 6 hours

High-dose pentobarbital coma: Children and Adolescents: Loading dose: 10 mg/kg over 30 minutes, then 5 mg/kg every hour for 3 hours; initial maintenance infusion: 1 mg/kg/hour; adjust to maintain burst suppression on EEG; maintenance dose range: 1 to 2 mg/kg/hour

Sedation of mechanically ventilated ICU patient (who failed standard therapy):

IV: Infants, Children, and Adolescents: Loading dose: 1 mg/kg followed by 1 mg/kg/hour infusion. Additional boluses at a dose equal to hourly rate may be given every 2 hours as needed. If greater than or equal to 4 to 6 boluses are administered within 24 hours, then increase maintenance rate by 1 mg/kg/hour; reported required range: 1 to 6 mg/kg/hour (median: 2 mg/kg/hour). Tapering of dose and/or conversion to oral phenobarbital has been reported for therapy greater than or equal to 5 days.

Usual Pediatric Dose for Status Epilepticus

Status epilepticus refractory to standard therapy:

Note: Intubation is required; dose should be adjusted based on hemodynamics, seizure activity, and EEG.

IV:

Infants, Children, and Adolescents:

Loading dose: 5 mg/kg

Maintenance infusion: Initial: 1 mg/kg/hour, may increase up to 3 mg/kg/hour (usual range: 1 to 3 mg/kg/hour); maintain burst suppression on EEG for 12 to 48 hours (no seizure activity), tapering pentobarbital rate by 0.5 mg/kg every 12 hours has been reported.

High-dose pentobarbital coma:

IV:

Infants and Children: Loading dose: 10 to 15 mg/kg given slowly over 1 to 2 hours; monitor blood pressure and respiratory rate.

Maintenance infusion: Initial: 1 mg/kg/hour; may increase up to 5 mg/kg/hour (usual range: 0.5 to 3 mg/kg/hour); maintain burst suppression on EEG.

Note: Loading doses of 20 to 35 mg/kg (given over 1 to 2 hours) have been utilized in pediatric patients for pentobarbital coma, but these higher loading doses often cause hypotension requiring vasopressor therapy.

Renal Dose Adjustments

Dosage should be reduced for patients with impaired renal function.

Liver Dose Adjustments

Dosage should be reduced for patients with hepatic disease.

Dose Adjustments

Dosage should be reduced in the elderly or debilitated because these patients may be more sensitive to barbiturates.

 

What other drugs will affect Nembutal Sodium?

Using Nembutal Sodium with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all other medications you use, especially:

doxycycline;

griseofulvin;

birth control pills or hormone replacement estrogens;

a blood thinner–warfarin, Coumadin, Jantoven;

an MAO inhibitor–isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others;

other seizure medications–divalproex, phenytoin, valproic acid (Depakene); or

steroid medicine–prednisone, dexamethasone, prednisolone, and others.

This list is not complete. Other drugs may interact with pentobarbital, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

 

NEGATIVE EFFECTS

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

confusion, agitation, hallucinations;

weak or shallow breathing;

slow heart rate, weak pulse; or

a light-headed feeling, like you might pass out.

Side effects such as confusion, depression, or excitement may be more likely in older adults and those who are ill or debilitated.

Common side effects may include:

drowsiness, dizziness;

loss of balance or coordination;

nausea, vomiting, constipation;

overactive reflexes;

sleep problems (insomnia), nightmares; or

feeling restless or excited (especially in children or older adults).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

 

Disclaimer

Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient.

Vigor Health Pharmaceuticals does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

 

BEST PLACE TO BUY  Nembutal

Here at Vigor Health Pharmaceuticals  we sell the best quality Nembutal and top quality pills.

Packaging:

We only use plain, discreet packaging without any branding or labels. In most cases package is sent as a gift in case of bigger packaging to rapidly aviate custom checks.

Delivery

100% delivery success rate with rapid delivery. 24hrs express and custom delivery ranging from 3-8 business days.

Reviews

There are no reviews yet.

Be the first to review “Nembutal Pentobarbital”

Your email address will not be published. Required fields are marked *

Close Menu
×
×

Cart